Personally I think your are over complicating the issue here.
I had the same issue and I replaced all the TRV's in my radiators with digital ones, not Zwave or networked but with a timer program.
They were about ?15($20) on Amazon.
I have higher setpoints in the morning/evening, and lower through the day and at night.
The only rooms without a trv are my bathroom and the hall where the thermostat is.
Now when the boiler kicks in the rooms already up to temperature don't heat any further.
Going down the route of smart trv's in each room or multiple thermostats etc can very expensive and complicated.
I now have a very comfortable house without having broken the bank.
The only down side I have is if one room is cold for whatever reason but the rest of the house is up to temperature the heating doesn't come on automatically.
In my mind this is good, as I might have one room where I've opened the window to air the room.
If I decide I do want to heat the room though I ask alexa to "torn on comfort mode".
This is a virtual switch that when on sets my thermostat setpoint higher for two hours.
This heats the hall, bathroom and any room currently below the TRV setting.